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AURORA Study
Data Repository
Data repository is unknown. Contact the manager to learn where to access the data.
Study Enrollment
Ongoing
Added on Portal
Jan 30, 2018

AURORA Study

Overview

The AURORA study represents a major national initiative to improve the understanding, prevention, and recovery of individuals who have experienced a traumatic event. This is the largest-ever study of trauma recovery involving 15+ emergency departments nation-wide. Five thousand participants who present to the emergency department for evaluation after trauma exposure will undergo a brief emergency department assessment of trauma-related, psychosocial, neurocognitive, and biological factors. Participants will be discharged with ecological monitoring, and will complete physiologic, biologic, neurocognitive, symptom, and health outcome assessments during one-year follow-up. Subsamples of study participants in Atlanta and Boston will undergo in-person deep phenotyping at 2 weeks and 6 months, consisting of biologic collection, functional magnetic resonance imaging (fMRI), and psychophysical evaluation. The wealth of first-in-kind information gained from this study will be used to overcome critical barriers to the prevention and treatment of common, morbid posttraumatic neuropsychiatric sequelae, and will allow the development of urgently needed preventive/treatment interventions for civilian and veteran populations that currently experience tremendous suffering.

Lead Scientist
Sam McLean, UNC
Meta Data
Number of Subjects 804
Primary Diagnoses
  • Anxiety
  • Posttraumatic stress
  • Depression
Species Human
Domains
  • Demographics, patient history or other descriptive data
  • Neuroimaging data
  • Biospecimens
  • Physiological data
  • Neurobehavioral or other outcome assessments
  • Wearables
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Keywords
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